Biological Effects of Man-Made Mineral Fibers. II. Their Genetic Damages Examined by In Vitro Assay.
نویسندگان
چکیده
منابع مشابه
Review of animal/in vitro data on biological effects of man-made fibers.
This paper reviews the investigations with man-made fibers (MMF). Insulation woods: glasswool (GW), rockwool (RW), slagwool (SW), glass microfibers (GMF), glass filaments (GFiI), and refractory ceramic fibers (RCF) have been used in experimental animals and in in vitro cell systems. A large heterogeneous number of fibers, methods of fiber preparation, size selection, aerosolization, fiber size,...
متن کاملDurability of ceramic and novel man-made mineral fibers.
In vitro solubility testing is an important means of assessing the likely behavior of fibers that are respired and accumulate in the lung. The problem has been that such tests often do not mirror the dissolution and removal mechanisms seen in vivo. Comparison of iron and silica solubility values of various types of mineral fiber showed no obvious correlation. Treating a mineral fiber containing...
متن کاملMan-made mineral fibers and the respiratory tract.
Man-made mineral fibers are produced using inorganic materials and are widely used as thermal and acoustic insulation. These basically include continuous fiberglass filaments, glass wool (fiberglass insulation), stone wool, slag wool and refractory ceramic fibers. Likewise, in the last two decades nanoscale fibers have also been developed, among these being carbon nanotubes with their high elec...
متن کاملIn vitro effects of mineral fibers.
In vivo tests available to determine the toxicity of mineral fibers are too expensive and time-consuming to be regularly employed in the evaluation of the potential health hazard posed by natural and man-made fibers. In vitro procedures, while economical, convenient and capable of ranking "relative toxicity," are uncertain predictors of specific lesions. Thus, it is of interest to compare the r...
متن کاملMan-made Mineral Fibres
practice, the detection Ii mit of scanning electron microscopy is about 0.1 j.m (Middleton, 1982). Transmission electron microscopy may be required to detect very thin fibres (Rood & Streeter, 1985). The elemental composition of individual fibres can be determined with an energy-dispersive X-ray ana1ysis attachment combined with an electron microscope (Middleton, 1982). Fibres are counted and s...
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ژورنال
عنوان ژورنال: INDUSTRIAL HEALTH
سال: 1999
ISSN: 0019-8366,1880-8026
DOI: 10.2486/indhealth.37.342